John and Jane Smith are a normal married couple, living a normal life in a normal suburb, working normal jobs...well, if you can call secretly being assassins "normal". But neither Jane nor John knows about their spouse's secret, until they are surprised to find each other as targets! But on their quest to kill each other, they learn a lot more about each other than they ever did in five (or six) years of marriage.
Brad Pitt
John Smith
Angelina Jolie
Jane Smith
Vince Vaughn
Eddie
Adam Brody
Benjamin Danz
Kerry Washington
Jasmine
Keith David
Father
Chris Weitz
Martin Coleman
Rachael Huntley
Suzy Coleman
Michelle Monaghan
Gwen
Stephanie March
Julie - Associate #1
Jennifer Morrison
Jade - Associate #2
Theresa Barrera
Janet - Associate #3
Perrey Reeves
Jessie - Associate #4
Melanie Tolbert
Jamie - Associate #5
Jerry T. Adams
Guard - Bull
Elijah Alexander
Marco Racin
Hans F. Alexander
Louis
Lauryn Alvarez
Coleman Kid #2
Burke Armstrong
Restaurant Patron
Ron Bottitta
P.J.
Earl H. Bullock
50's Man
Miguel Angel Caballero
Bellboy - Bogotá
Victor A. Chapa
Americana Hotel Manager
Maree Cheatham
Father's Secretary
Laine Collins
Eddie's Waitress
Noah Dahl
Coleman Kid #1
Merrilee Dale
Mom #2
Chris Daniels
Mailman Assassin
Patrika Darbo
50's Woman
Jennifer DeMille
Breakfast Diner Waitress
Tyce Diorio
Salsa Dancer #2
Patricia Donaldson
Louise
Sabi Dorr
Bodyguard #3
Greg Ellis
Mickey
David Escobedo
Americana Hotel Bartender
Kaela Freeman
Neighborhood Girl
Megan Gallagher
40's Woman
Amy Hathaway
Beauty
Jessica Hedden
Hopskotch Girl #2
Kathrine Herzer
Hopscotch Girl #1
Nigel Hudson
Boxing Sparring Partner
Ravil Isyanov
Curtis
Stephanie Ittleson
Party Guest
Mark Ivanir
Patron - Dive Bar
Benton Jennings
Maitre'D
Simon Kinberg
Investment Banker #1
Peter Lavin
Leroy
Deren Tadlock
Doorman
Sean Mahon
Lucky
Kevin Makely
Johnson
Mike McCaul
Bill the Neighbor
Derek Medina
Policia #2
Will Moore
House Assassin #1
Joel Munoz
Policia #1
Mark Newsom
Guard #1
Richie Ornelas
Policia #4
Jordan Osher
House Assassin #2
Edward Padilla
Colombian Military Officer
Eugene C. Palmer
Judge
Luis Racer
Policia #3
Liz Ramos
Salsa Dancer #1
Leonard Robinson
Watchguard
Felix A. Ruiz
Vocalist
Sam Sabbah
Bodyguard
Kim Schioldan
Bartender - Dive Bar
Ty Sharp
Towncar Driver
Jimmy Shubert
Ancient Barker
Abigail Rose Solomon
Mom #3
Hannah Von Kanel
Hopskotch Girl #3
Ali Marsh
Mom #1
Kim H. Winther
Mr. Smith's Father
Michael Winther
Investment Banker #2
Michael-John Wolfe
Bartender - Coleman House
Jeff Yagher
40's Man
Bryan Anthony
Dancer
Douglas Caldwell
Dancer
R.J. Durell
Dancer
Melissa Hurley
Dancer
Jacqui Landrum
Dancer
Carol Mack
Dancer
Michael Morris
Dancer
Gloria Rodriguez
Dancer
Linda Kathleen Taylor
Dancer
Anne Vardanian
Dancer
Ara Vardanian
Dancer
Luis Vasquez
Dancer
John W. Woodruff
Dancer
Angela Bassett
Mr. Smith's Boss (voice) (uncredited)
William Fichtner
Dr. Wexler - Marriage Counselor (voice) (uncredited)
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